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KMID : 0363220090470010071
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Korean Journal of Dermatology
2009 Volume.47 No. 1 p.71 ~ p.74
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A Case of Pseudolymphoma Syndrome Induced by Vancomycin
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Kim Sang-Tae
Baek Jae-Woo
Kim Tae-Kwon
Lee Jin-Woo
Roh Hyo-Jin
Suh Kee-Suck
Jeon Young-Seung
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Abstract
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We report here on a case of a patient who experienced fever, skin eruption and lymphadenopathy 1 month after the
beginning of vancomycin treatment. Generalized mild pruritic erythematous pin-head to rice-grain sized confluent
scaly papules and plaques appeared on the whole body. Skin biopy showed the characteristic findings of pseudolymphoma
mimicking mycosis fungoides. The skin lesions and general symptoms improved after discontinuation of vancomycin
and starting steroid therapy. The patient was diagnosed with pseudolymphoma syndrome due to vancomycin.
Pseudolymphoma syndrome shows clinical features that are different from those of usual drug eruptions, and the
histologic findings are similar to mycosis fungoides. Thus, a thorough understanding of the clinical and histologic
features of this entity may aid making a diagnosis, establishing treatment plans and determining the prognosis.
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KEYWORD
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Pseudolymphoma syndrome, Vancomycin
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